always thought that 天時、地利、人和 is used when it refers to success not easily achievable, but many factors have to be aligned, many at times by chance. and the lack of one will result in non-success.
based on an incident that took place these two days, it seems that 天時、地利、人和 can cause a total failure, breakdown, or downfall. the lack of one, the failure/breakdown/downfall just wouldnt be complete or happen at all :O
must also credit 安琪 as the indirect source of inspiration (: